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Job Details

Senior Research Associate/Scientist Analytical Development

Location
South San Francisco, CA, United States

Posted on
Feb 27, 2022

Apply for this job






Profile

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**MEMBERS ONLY**SIGN UP NOW***. is a clinical-stage, next-generation gene editing company harnessing high efficiency targeted gene integration to develop a new class of therapies to potentially cure a wide range of serious and life-threatening diseases. **MEMBERS ONLY**SIGN UP NOW***. is pioneering a precision gene editing approach that could enable a variety of applications to transform human health through its potential to achieve one of medicine’s most elusive goals: to precisely “find & replace” any gene in the genome. **MEMBERS ONLY**SIGN UP NOW***.’s platform allows it to precisely correct mutations, replace entire disease-causing genes with normal genes or insert new genes into predetermined, safe locations. The company was co-founded by academic pioneers in the fields of gene editing and gene therapy, including Maria Grazia Roncarolo, M.D., and Matthew Porteus, M.D., Ph.D.

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Learn more about **MEMBERS ONLY**SIGN UP NOW***. by visiting ****target=_blank rel=no-follow>****following the company on ****target=_blank rel=no-follow>LinkedIn.

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The Role:

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 We are seeking a talented Senior Research Associate/Scientist to join the AD/QC team in the Technical Operations organization. The candidate will be responsible for developing physiochemical methods that will be used to develop a robust manufacturing process and characterize our gene-edited cell therapy products. Characterization of intermediates, gene editing components, and residual impurities are also in scope. The candidate should enjoy working with cross-functional teams and will need to collaborate with colleagues in process development, manufacturing, quality, regulatory, and research.

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What You Will Do:

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  • Develop analytical methods for viral vectors, oligonucleotides, proteins, and RNP complexes
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  • Develop analytical methods for in-process testing and measuring residual impurities
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  • Establish new analytical capabilities through on-site work, collaboration with vendors, and adoption of novel technologies
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  • Represent AD on cross functional teams or with external partners
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  • Design and execute experiments, analyze data, and present results to CMC teams
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  • Write SOPs, test methods, and other documents that will support regulatory filings
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What You Will Bring:

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  • BA./B.S., MS or Ph.D. in Chemistry, Biochemistry, or other natural science with 2 years of biotech experience in development or QC roles. The candidate’s combination of education and experience will be considered.
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  • Enthusiastic, patient focused, and passionate about science and regenerative medicine
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  • Broad familiarity with physiochemical, biophysical, and immunochemical methods including: electrophoresis, chromatography, spectroscopy, mass spectrometry, light scattering, ELISA, and western blots
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  • Expertise in one or more of the above methods
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  • Excellent written and oral communication skills
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  • Highly competent with various data acquisition and analysis software packages
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  • Resourceful and creative problem solver
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nFit with **MEMBERS ONLY**SIGN UP NOW***.’s culture:n
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  • Ability to build strong relationships with co-workers of various backgrounds and expertise
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  • Ability to function at a high level in a team setting whether leading the group or acting as an individual
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  • contributor
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  • Values-based leadership consistent with **MEMBERS ONLY**SIGN UP NOW***.s’ Core Values
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  • Excitement about the vision and mission of **MEMBERS ONLY**SIGN UP NOW***. 
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  • Flexibility
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  • Integrity
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nCompensation/ Benefits:n
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  • Competitive salary with equity 
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  • Health benefits
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n n**MEMBERS ONLY**SIGN UP NOW***. is an equal opportunity employer, and all qualified applicants will receive consideration fornemployment without regard to age, race, color, religion, sex, sexual orientation, gender identity, nationalnorigin, protected veteran status, or disability status, or any other characteristic protected by law.n nTo all recruitment agencies: **MEMBERS ONLY**SIGN UP NOW***. does not accept agency resumes or applications. Please do not forward resumes to our jobs alias, or **MEMBERS ONLY**SIGN UP NOW***. employees. **MEMBERS ONLY**SIGN UP NOW***. is not responsible for any fees related to unsolicited resumes or applications.n,identifier:{name:**MEMBERS ONLY**SIGN UP NOW***.,value:4318291004,@type:PropertyValue},datePosted:2022-02-28T02:46:39 00:00,validThrough:2022-03-30T03:59:59 00:00,employmentType:FULL_TIME,hiringOrganization:{name:**MEMBERS ONLY**SIGN UP NOW***.,@id:2232534,url:****San Francisco, CA,address:{addressCountry:US,addressLocality:California,addressRegion:California,postalCode:94080,@type:PostalAddress},@type:place},industry:Information Technology, Business/Data Analytics, Science/R&D, Biotechnology,workHours:Full time,educationRequirements:Bachelors Degree,@type:JobPosting,@context:****

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