Senior Research Associate DNA Systhesis

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Position

Senior Research Associate, Non-Viral Delivery Technologies

Job Description

The Cell Therapy Technology & Platforms group is seeking an enthusiastic, self-driven individual to join its innovation-focused, multi-disciplinary team focused on advancing new, enabling technologies. As a member of the Gene Editing and Delivery Technology team, the successful candidate will support the advancement of non-viral delivery technologies. Activities will include cloning, large-scale nucleic acid generation and purification, primary cell culture and transfection, and multicolor flow analysis. The position will require experimental design, experimental execution, data analysis, drafting of technical reports, and presentation of results.

Education


A degree in biology, cell biology, microbiology, immunology, bio/chemical engineering or a related scientific field
Bachelors plus 2 or more years of relevant experience
Masters plus 1 more or years of relevant experience


Experience


Experience with molecular cloning techniques (standard cloning, Gibson assembly)
Experience with nucleic acid manipulation (bacterial production, PCR, in vitro transcription) and analysis (Sanger sequencing or NGS, nanodrop, electrophoresis, etc.)
Experience with nucleic acid purification (precipitation, chromatography, etc.)
Experience in executing and analyzing data from bioassays

1 year of mammalian or primary cell culture laboratory experience

Experience with writing technical documents for interdepartmental use
Basic knowledge of cell therapy development


Duties and Responsibilities


Support technology development and on-going activities with external collaborators and service providers (CMOs, CROs)
Work with internal collaborators including Research, Supply Chain, and other stakeholders to evaluate novel gene constructs, synthesis methods, and production technologies
Generate material (DNA, RNA, ribonucleoproteins) to support technology development.
Develop processes for large-scale nucleic acid generation and purification
Analyze data from cell functionality or chemical assays.
Write technical reports including development reports and Standard Operating Procedures.
Supporting lab functions including restocking consumables, maintaining equipment, and cleaning.
Up to 5% of time may be spent travelling outside of the city or country.


Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Company: Bristol-Myers Squibb

Req Number: R1522210_EN

Updated: 2020-03-09 00:00:00.000 UTC

Location: Seattle,Washington

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

Company info

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