Senior Associate Scientist

Profile

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

POSITION

Senior Associate Scientist

SUPERVISOR

Steven Saenz, Senior Scientist

DEPARTMENT

Discovery Biology Immunology, ICFG TRC

Prerequisites:

Bachelor's degree in a scientific discipline with at least 8 years work experience or Master's degree with at least 6 years work experience.

Summary/Scope

The Discovery Biology Immunology group is seeking a self-motivated, energetic, detail-oriented candidate with strong background in cellular immunology and molecular biology. The focus of this position will be to develop and perform assays using human blood/biopsies or rodent blood/tissues that will help in determining the extent of target engagement achieved by drug development candidate molecules for auto-immune and inflammatory diseases. The individual will participate in a broad range of programs including Cellular Therapy (CAR T cells) and bispecific-antibodies modalities, assessing target cell depletion, adaptive immune activation and cell cytoxicity. Individuals will work in a dynamic, small research group and must be comfortable working in a fast paced environment. Strong problem-solving and time management skills are essential to complete diverse assigned tasks. Industry experience is preferred.

Responsibilities will include, but are not limited to, the following:

Design, plan, and execute blood/tissues based assays and troubleshoot existing protocols Perform high quality and well controlled immunological assays with human and animal blood or tissues including cell stimulation, cytokine analysis, and flow cytometry with minimal supervision Support scientists in execution of proof-of-concept studies. Generate and independently analyze multi-parameters data sets using appropriate analytic programs Maintain well written and accurate research electronic notebook detailing work undertaken Comply with laboratory safety procedures

Skills/Knowledge Required :

Experience in working with blood and tissues from human and animal for the study of immunological/inflammatory responses Strong hands-on experience with immune cell activation and characterization assays, multi-parameter flow cytometry, Luminex, MSD assay, ELISA, ELISpot, RT-PCR, DNA/RNA preparation, immunoprecipitation, and western blotting. Prior work with CAR-T cell production, assays & characterization preferred but not required Prior work with lentiviral construct design, generation and cell transductions desired Proficiency with FlowJo, Prism, and Microsoft office applications Possess a thorough knowledge of experimental design and underlying scientific principles Excellent organizational, record keeping, oral and written communication skills Team player, detail oriented and organized

Qualifications:


Bachelor's degree in a scientific discipline with at least 8 years work experience or Master's degree with at least 6 years work experience.


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Company: Bristol-Myers Squibb

Req Number: R1527645_EN

Updated: 2020-07-16 00:00:00.000 UTC

Location: Cambridge,Massachusetts

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

Company info

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