Associate Scientist or Senior Research Associate AAV Vector Analytics

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Bristol-Myers Squibb (BMS) is developing novel cellular immunotherapies based on two distinct and complementary platforms – Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body’s immune system to treat cancer.

BMS is seeking a Senior Research Associate/Associate Scientist to join the Vector Analytics group within the Analytical Development Department to develop methods for AAV vectors. The successful candidate will join a team performing method development for viral vectors as key intermediates in cellular therapy drug products. The position will report to head of the Viral Vector Analytics team and spend the majority of his/her time in the laboratory

Job Description:


Establish analytical methods for AAV vectors, including biochemical, molecular, and biophysical assays

Design, execute, and analyze method development experiments

Document experiments in electronic lab notebook system

Perform qualification studies for AAV methods per established guidance

Develop control strategy for analytical methods including the establishment of control ranges

Author, review and approve technical documents including standard operating procedures, test methods, and technical reports

Present findings to Vector analytics teama and other relevant internal groups


Basic Qualifications:


Senior Research Associate: B.S. degree in a scientific or engineering discipline with 4 years (or M.S. 2 years) of relevant experience in analytical methods

Associate Scientist: B.S. degreen in scientific or engineering discipline with 6 years (or M.S. 4 years) of relevant experience in analytical methods

Demonstrated ability with cell culture, DNA and RNA isolation, viral/vector transduction, qPCR and RT-qPCR, and ELISAs





Ability to work in a fast-paced environment, meet deadlines, and prioritize work on multiple projects

Strong communication skills in technical writing and oral presentation


Preferred Qualifications:


Proficiency with software including GraphPad, SoftMax, VectorNTI, and Geneious

Understanding of ICH/FDA/EMEA regulations and guidance for analytical methods

Background in virology or viral vector biology

Familiarity with flow cytometry methodology and software

Experience interfacing with research organizations and GMP test laboratories


Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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