Principal Scientist - Assays and Data Analysis

Profile

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science.In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Job description

We are seeking an enthusiastic, experienced, and creative Senior Research Scientist with experience in assay design and assay data analytics to join the Antibody Generation team. The candidate will be expected to spear-head the set-up of functional assays for binder characterization, perform screening to identify relevant lead candidates and help disseminate protocols the team. Deep understanding of assay design, statistics as well as data aggregation and visualization is required. The candidate will be expected to identify assay improvements and drive optimization from the lab bench, and work with the Automation team to make assays amenable for high-throughput screening. Teaching and supervision of junior scientists may be part of the role.

Responsibilities:

• Establish functional mechanism-of-action assays to identify leads.
• Closely collaborate with fellow team members to execute screening for BMS lead programs and disseminate protocols to fellow team members.
• Assay optimization and collaboration with the Automation team to make assays amenable to high-throughput execution
• Trouble-shoot and optimize protocols and propose creative solutions to improve efficiency to existing processes.
• Collaborate with functional screening groups across departments as well as IT to improve data management and decision making in hit/lead selection
• Analysis of big data sets across programs to establish patterns and predictiveness of read-outs
• Excellent written and oral skills are necessary
• Accomplish goals under project team time lines
• Provide technical guidance to team members; may supervise/teach junior staff

Qualifications:

• Ph.D. or advanced degree in Molecular and Cell Biology, Biotechnology or related field with 2 to 5 years of relevant experience.
• Extensive experience in Elisa, flow cytometry, and imaging based cellular assay formats
• Statistical knowledge to enable analysis of assay data for robustness and accuracy
• Experience in cell culture, cell based immune activation assays and antibody sequence analysis is desirable.
• Experience in aggregating and statistical analysis of assay data from automated systems, visualization of large datasets, and assign thresholds to identify leads is required.
• Excellent time management, record keeping and organizational skills.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to **** target=_blank rel=no-follow>****. Visit****target=_blank rel=no-follow> careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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