Stromal Discovery Biology Lead Tumor Microenvironment Modulation TRC

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

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(Senior Director/Director Level)

Position Summary

Lead the stromal biology-associated portion (both small and large molecule) of the preclinical drug development programs for the Tumor Microenvironment Modulation (TME) Thematic Research Center (TRC) which which develops therapeutic targets at the intersection of tumor, stromal and immune biology with the TME to enhance responsiveness to checkpoint blockade and other targeted therapies.

Roles & Responsibilities

Lead of team of 10-20 scientists and effectively collaborate with other TME Modulation TRC discovery and discovery translational biology colleagues as well as colleagues in supportive line functions (including discovery biotherapeutics, small molecule drug discovery, translational medicine, early clinical development and project leadership) to advance preclinical development of therapeutic candidates to early clinical development.

Collaborate with both local and global bioinformatics as well as translational medicine colleagues to generate testable hypotheses for targetable tumor-associated stromal nodes and pathways within the tumor microenvironment that drive resistance to current immunotherapies.

Scientific Foci:

Fibroblast biology

Wound healing biology

Suppressive stromal factors

Senescence biology

Experience


Ph.D. with at least 8 years of relevant industrial experience in Stromal, Fibroblast and wound healing biology or closely-related fields

Biology drug hunting expertise needed to lead both small and large molecule programs from early target identification through to IND submission

A proven track record in the field, as evidenced by publication and/or patent record


Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Company info

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