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Job Details

Scientist AAV Analytical Development

Location
Seattle, WA, United States

Posted on
May 01, 2020

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Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Bristol-Myers Squibb (BMS) is developing novel cellular immunotherapies based on two distinct and complementary platforms – Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body’s immune system to treat cancer.

BMS is seeking a Scientist with experience in adeno-associated viral (AAV) methods to join the Vector Analytics group within the Analytical Development Department. The successful candidate will develop, optimize and perform troubleshooting for analytical methods for AAV vector characterization and release testing. The Scientist will report to head of the Viral Vector Analytics team.

Job Description:


Lead the successful design, execution, analysis and documentation of experiments to develop analytical methods for AAV vectors

Oversee the qualification of vector analytical methods

Author, review and approve technical documents including standard operating procedures, test methods, and technical reports

Present findings on method development provide interpretation related to vector product quality to cross-functional teams

Participate in program teams to design and execute CMC activities to support cell therapy product development

Contribute to the development of novel technologies for gene and cell therapy


Basic Qualifications:


M.S. degree in virology, analytical sciences, or related field with 8 years of relevant experience or Ph.D. in relevant field with 2 years of experience

Proven track record in method development, including experimental design, execution and evaluation

Knowledge of and experience with viral vectors (lentiviral and AAV)

Experience with ddPCR as well as qPCR, nucleic acid isolation, cell culture, ELISAs, and viral transduction





Ability to work in a fast-paced environment, meet deadlines, and prioritize work on multiple projects

Strong communication skills in technical writing and oral presentation


Preferred Qualifications:


Track record of participation in cross-functional teams

Familiarity with gene editing technologies

Experience authoring technical and regulatory documents

Experience interfacing with research organizations and GMP test laboratories


Bristol-Myers Squibb (BMS) is developing novel cellular immunotherapies based on two distinct and complementary platforms – Chimeric Antigen Receptors (CARs) and T Cell Receptors (TCRs) technologies. Our goal is to revolutionize medicine by re-engaging the body’s immune system to treat cancer.

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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