Associate Scientist / Scientist I Discovery Biology

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Associate Scientist / Scientist 1 (Discovery Biology)

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**MEMBERS ONLY**SIGN UP NOW***. is a clinical-stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological disease. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity for a junior scientist to join a team, work on transformative science, and take part in building an exciting, science-driven company and develop groundbreaking cell therapy products.

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Responsibilities:

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• Collaborate in a team to develop next-generation cell products for the clinical pipeline.
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• Apply gene editing, viral gene delivery, and/or chemical screens to develop neuronal cell products with reduced immunogenicity, enhanced potency and/or accelerated maturation.
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• Develop cell-based assays to test and validate hypotheses.
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• Characterize cell products (immuno cyto-chemistry, Flow cytometry, RT-QPCR, RNA sequencing).
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• Conduct fluorescence- or magnetic -activated cell sorting experiments.
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• Maintain human pluripotent stem cells and differentiate into a variety of neuronal lineages utilizing scales from 384 well plates to regular and large-scale culture vessels.
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• Identify lead methods and conduct validation and scale up experiments. Collaborate with Process and Preclinical departments to support disease modifying activity studies in animal models.
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• Maintain detailed records, perform data analysis, and report results during team meetings
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Required Qualifications:

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• PhD ( 0-3 years of relevant experience) or Master's degree ( 6-8 years of relevant experience) in cell and molecular biology (or a related field).
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• Hands on experience with human stem cell culture maintenance and in vitro differentiation.
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• Expertise in at least one area of: neuroimmunology/neuro inflammation, neurodevelopmental biology, or CRISPR screens
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• Proven scientific achievements by high publication records
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• Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance research productivity.
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• High integrity, great organization and ability to multitask while working within fast-paced timelines
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• Critical thinking, strong team player and problem-solver
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• Excellent writing, verbal communication, and interpersonal skills
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• Willing to work a limited number of hours on some weekends.
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Preferred Qualifications:

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• Knowledge in neuroscience and human developmental biology
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• Experience in cell assay development, immunohistochemistry, and flow cytometry analysis
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• Experience in high content microscopy/screening, CRISPR screens, calcium imaging or MEAs (multi-electrode arrays) is a plus.
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For immediate consideration, please email your resume to: **** rel=no-follow>****. Interested in learning more about our science and our team? Please visit our website at ****rel=no-follow>****is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

,datePosted:2022-03-03T04:10:35 00:00,validThrough:2022-04-02T03:59:59 00:00,employmentType:FULL_TIME,hiringOrganization:{name:**MEMBERS ONLY**SIGN UP NOW***.,@id:398414,url:****San Francisco,address:{addressCountry:US,addressLocality:California,addressRegion:California,postalCode:94080,@type:PostalAddress},@type:place},industry:Science/R&D, Biology, Biotechnology,workHours:Full time,educationRequirements:Doctorate/PHD/MD,@type:JobPosting,@context:****

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