Associate Scientist Gene Edited Platform

Profile

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

PURPOSE AND SCOPE OF POSITION:

Key contributor to the development of Chimeric Antigen Receptor (CARs) and T Cell Receptors (TCRs) phase-appropriate manufacturing processes. This role will be responsible for phase-appropriate process development strategy formulation with support from manager/senior member of the team and drafting of appropriate regulatory filings. This role will mentor junior members in the team and will support the planning, design and execution of development experiments to enable robust manufacturing process design.

DUTIES AND RESPONSIBILITIES:


Will be part of a CMC team and will be responsible for the strategy and development of phase-appropriate manufacturing process platforms with support from manager/ senior member of the teams. In this role you will also bring in innovation and next generation technologies into the platform work.
Design complex T-Cell experiments using sound scientific principles to support cell therapy process development and characterization.
Maintain proficiency in data analysis and effective data presentation within a cross functional team setting.
Influence and assist in the management of efficient Design of Experiments (DOE) in order to ensure efficient process development effort.
Troubleshoot and solve technical problems of moderate scope with minimal help from their manager
Strong collaboration across departments to participate in appropriate regulatory filing activities.
Timely and thorough documentation and completion of electronic laboratory notebooks
Author and review technical reports detailing experimental work and summarizing results
Maintain a safe work environment in accordance with policies/procedures/regulations
Mentorship of junior member of the team or direct reports
Supporting lab functions-including, but not limited to restocking consumables, maintaining equipment and cleaning
Flexibility with work schedule as maintenance of cell cultures on occasional weekends, early mornings, or evenings is required


REQUIRED COMPETENCIES: Knowledge, Skills, and Abilities:

Education:

BS with 5 years of experience or MS with 4 years of experince in Biological/Chemical Engineering, Biotechnology, Biology or a relevant scientific discipline

Required skills:

2-5 years of mammalian or primary cell culture laboratory experience

Preferred skills:


Basic knowledge of immunology
Experience with T-cell selection, viral transduction, non-viral gene delivery, gene editing technologies, T-cell expansion and cryopreservation
Experience in executing and analyzing data from multicolor flow cytometry or bioassays
Familiar with design of experiment approaches and statistical analysis of data
Ability to work independently in a fast-paced team environment, meet deadlines, prioritize work across multiple projects
Ability to manage uncertainties in projects and schedule
Leadership experience for junior lab staff
Ability to learn new technologies and acquire knowledge quickly in the rapidly expanding adoptive T-cell therapy field


WORKING CONDITIONS (US Only):

Work to be performed in a both a standard office setting as well as BSL-2 laboratory settings, which will require occasional need to lift/carry a maximum weight of 10lbs.

This job description is intended to describe the general nature and level of work being performed by the person assigned to this position. The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Company: Bristol-Myers Squibb

Req Number: R1526882_EN

Updated: 2020-06-24 00:00:00.000 UTC

Location: Seattle,Washington

Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.

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